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Natural Prodcast is a podcast about natural products and the science and scientists of secondary metabolism. Natural products, secondary metabolites, specialized metabolites -- whatever you want to call them, they're the chemicals that make species unique and different from one another, and are incredibly important to medicine, the environment, and human health. Dan Udwary introduces concepts in this exciting field, and talks to the fascinating scientists who work in it. This series brought to you by the US Department of Energy Joint Genome Institute.
In this episode, Dan and Jackie talk to Alison Narayan, from the University of Michigan's Life Sciences Institute and Department of Chemistry. We talked broadly about the field of "biocatalysis", about her DNA synthesis project with the JGI to explore flavin monooxygenases, and what we all need to do in the future to figure out how to make predictions about the functionality and chemical capabilities of enzymes. Also, the Prodcast formally declares its position on candy corn.
Natural Prodcast's interview with Elizabeth (Betsy) Parkinson, from Purdue, about bacterial signaling molecules and regulation of biosynthetic pathways, semisynthetic cyclic peptides, student mental health, and getting kids interested in microbiology.
Natural Prodcast's interview with Vanderbilt Professor of Chemistry, Brian O Bachmann.
Natural Prodcast talks to Prof William Fenical of Scripps Institution of Oceanography in San Diego about the beginnings of marine natural products, his experiences in drug discovery, and exploring marine bacteria.
It's a crossover episode! Menaka Wilhelm, from JGI's Genome Insider, and I talk about how to work with the JGI, specifically in the form of the Community Science Program, or CSP. We talked to Deputy of User Programs, Tanja Woyke and Project Manager Miranda Harmon-Smith about all the details of what makes a good CSP, how to apply for one, and what happens once it starts.
Natural Prodcast's Dan and Alison talk to Dr Cassandra Quave of Emory University, and author of The Plant Hunter. Transcript at https://jgi.doe.gov/natural-prodcast-episode-17-cassandra-quave/
Natural Prodcast presents our interview with Professor Marcy Balunas, currently at the University of Connecticut's Department of Pharmaceutical Sciences but soon moving to the University of Michigan's Department of Microbiology and Immunology. In this episode, we discuss her work in in many areas of chemical exploration of natural products for bioactive compound discovery, understanding symbiosis, and a JGI project around ants and their fungus farms. Transcript at https://jgi.doe.gov/natural-prodcast-episode-16-marcy-balunas/
This is Natural Prodcast's conversation with Professor Katherine Duncan from the University of Strathclyde in Glasgow, Scotland. Dr Duncan's work focuses on marine microbial chemical ecology. We also discuss Actinobase, molecular networking, and the future of integrated secondary metabolism data. Transcript at https://jgi.doe.gov/natural-prodcast-episode-15-katherine-duncan/
Our guest on this episode is Dr Nigel Mouncey, JGI's Director, and also lead of the JGI's Secondary Metabolites Science Program. Since his arrival in 2017, Nigel has led a vision for the JGI that sees secondary metabolism analysis and research as a driver for novel technologies that can serve all JGI users. Nigel has a long scientific background in pathway and gene regulation, and a distinguished career in industry developing natural products for commercial use. Transcript at https://jgi.doe.gov/natural-prodcast-episode-14-nigel-mouncey/
In this episode of the podcast, we talked a lot about terminology, especially around "secondary metabolism" versus "specialized metabolism" and "primary metabolism" versus "centralized metabolism" and why and how they're different when we take things from a human-centric view rather than a microbe-centric one. It was so fun, and I learned a ton. I hope you will too! Transcript at https://jgi.doe.gov/natural-prodcast-episode-13-francisco-barona-gomez/
Amanda is a wife. A mother. A blogger. A Christian.
A charming, beautiful, bubbly, young woman who lives life to the fullest.
But Amanda is dying, with a secret she doesn’t want anyone to know.
She starts a blog detailing her cancer journey, and becomes an inspiration, touching and
captivating her local community as well as followers all over the world.
Until one day investigative producer Nancy gets an anonymous tip telling her to look at Amanda’s
blog, setting Nancy on an unimaginable road to uncover Amanda’s secret.
Award winning journalist Charlie Webster explores this unbelievable and bizarre, but
all-too-real tale, of a woman from San Jose, California whose secret ripped a family apart and
left a community in shock.
Scamanda is the true story of a woman whose own words held the key to her secret.
New episodes every Monday.
Follow Scamanda on Apple Podcasts, Spotify, or wherever you listen.
Amanda’s blog posts are read by actor Kendall Horn.
